Thursday, April 23, 2009

The Immoral Research That Would be Required to Make "Reproductive Cloning" Safe

In my last SHS post, I deconstructed the "ethical" objections of "the scientists" to reproductive cloning as really being about safety, not the inherent wrongness of human cloning itself. (Reproductive cloning is actually a misnomer. The act of cloning is somatic cell nuclear transfer, which asexually creates an embryo. So what we are really talking about is the use to which the human life created through cloning would be put). Animal cloning leads to many miscarriages and birth defects, and thus there is near universal agreement that reproductive cloning should not be tried--for now.

But if those problems could be overcome, I see no reason for believing that "the scientists" would still say no. In fact, is suspect they'd be tripping over each other to do it.

What would it take to make reproductive cloning "safe?" Scientists would have to repeatedly clone and destroy thousands and thousands of embryos and fetuses. I asked Dr. David Prentice for my book Consumer's Guide to a Brave New World, what the process would likely be. From my book:

He [Prentice] described for me the intense research trial-and-error approach that would be required to learn how to safely engage in cloning-to-produce-children: "Scientists would have to clone thousands of embryos and grow them to the blastocyst stage to ensure that part of the process leading up to transfer into a uterus could be "safe,” monitoring and analyzing each embryo, destroying each one in the process. Next, cloned embryos would have to be transferred into the uteruses of women volunteers. The initial purpose would be analysis of development, not bringing the pregnancy to a live birth. Each of these clonal pregnancies would be terminated at various points of development, each fetus destroyed for scientific analysis. The surrogate mothers would also have to be closely monitored and tested, not only during the pregnancies but also for a substantial length of time after the abortions.

Finally, if these experiments demonstrated that it was probably safe to proceed, a few clonal pregnancies would be allowed to go to full term. Yet even then, the born cloned babies would have to be constantly monitored to determine whether any health problems develop. Each would have to be followed (and undergo a battery of tests both physical and psychological) for their entire lives, since there is no way to predict if problems [associated with gene expression] might arise later in childhood, adolescence, adulthood, or even into the senior years."


The absurdity, not to mention the immorality, of treating human life as mere detritus to be experimented upon and tossed aside if it doesn't have the proper (gene) consistency, should be self-evident. It would permit us to transform cloned human beings into life-long medical experiments. No wonder the President's Council [on Bioethics] report was so unequivocal in its condemnation of attempting cloning-to-produce children!

Much of this work would probably be done in artificial wombs. But that wouldn't change the nature of the sheer immorality of the experiments.

And consider this: If we reject human exceptionalism this becomes doable. For example, if purported "personhood" rather than "humanhood" comes to matter morally, scientist would be empowered to experiment on human fetuses--perhaps even infants--as much as they wanted and it wouldn't matter.

Much is at stake in how we harness--and control--the awesome power of biotechnology. The principles we apply to determine what is ethical and what is not make all the difference in the world about the kind of society we will become.

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9 Comments:

At April 23, 2009 , Blogger Dark Swan said...

I completely disagree with Prentice.

With the advent of IPS cells, there would be no need for an egg or an embryo to create reproductive clones.

You mention artificial wombs. hIPS cells are clones capable of giving rise to an entire person if gestated. When artificial wombs are engineered you will then have to acknowledge a lack of foresight in conceiving the viability of IPS cells as whole organisms. IPS clones will be able to become a fetus easier than SCNT clones.

I believe the ability to manipulate transcription factors to promote organismic growth of specific body parts will be even more complex than growing IPS cells into an entire fetus. Figuring out these factors is highly likely.

Artificial wombs would possibly already be reality if reproductive cloning was a goal of the Scientific community. Just look at the astonishing progress already made by Direct Reprogramming.

The failure of this blog and all others who toe the line for the pro-life community who have refused to consider that IPS cells have the capacity to yield a complete being will be exposed for the lack or vision. What Prentice postulates is way off target IMHO.

 
At April 23, 2009 , Blogger HistoryWriter said...

Re: "humanhood" v. "personhood", the argument has already been settled. The 14th Amendment protections of life, liberty and property apply only to citizens, and a citizen is defined in the same Amendment as one either "born or naturalized." Accordingly, neither an embryo nor a fetus qualifies as a legal person in American jurisprudence. You can always hope the Constitution will be amended to grant legal personhood under some other circumstance, but I wouldn't count on it.

 
At April 23, 2009 , Blogger Wesley J. Smith said...

History Writer: That just isn't true. For example, the Feds passed a law protecting embryos/fetuses except in the abortion context. Many states punish the death of fetuses as murder and those murder convictions have been upheld in appeals courts.

The Amendments had nothing to do with the issue raised here. It had to do with the rights of African-Americans in the post slavery era. The rights of the unborn were never considered, either pro or con.

 
At April 23, 2009 , Blogger John Howard said...

I think a federal law against artificial wombs would be easy to pass, too. Why should it be allowed? It is inhuman. There is no right for anyone to create a human person in an artificial womb. Let's just take that terrible option off the table for good, why not?

 
At April 23, 2009 , Anonymous Anonymous said...

Re : 14th Amendment

It isn't as cut and dry as you would like to make it appear, History Writer. Many southern states have used the 14th Amendment as a prop to give "citizenship" (in the form of temporary social security numbers and services) to the embryo's and fetus's of illegal immigrants. This allows the states to "legally" grant services to the non-citizen mother, as they are the "home" for the citizen unborn.

Simply put, we use the 14th Amendment as we see fit, when we see fit, to distort existing laws and cover those that are not necessarily covered by other aspects of Constitution or law.

 
At April 23, 2009 , Blogger Don Nelson said...

John, I think SHS reported some time ago that much of the work and intent on artificial wombs is to prevent miscarriage or save a baby being miscarried. That is, they would be used to keep the unborn baby boy or girl from dying. That sort of seems miraculous to me, but it could definitely be used for evil purposes like using them for hatcheries.

 
At April 24, 2009 , Blogger John Howard said...

I think there's got to be a difference between an incubator for premature babies and an artificial womb. Maybe the distinction is simply that incubators are designed for living babies that came to life in a woman's womb, while artificial wombs are for bringing an embryo to life, that is, the heartbeat hasn't started yet, and the idea is that the heart will develop and start beating outside a woman's womb.
I think society ought to be able to stop incubators from receiving any more research funding or insurance funds, so that they simply don't work for very premature babies, creating a limit based on resources. We shouldn't have to prioritize allowing three week old fetuses to survive outside the womb, we've gone far enough in that direction, it should be a resource-allocation decision to say enough.

 
At May 01, 2009 , Blogger Michele Shoun said...

Is Dark Swan correct about hIPS cells being clones? I've read Dianne Irving's discussion of the distinction between cells and organisms (http://www.wesleyjsmith.com/blog/2009/04/nature-decries-attempts-to-redefine.html), and a statement by Do No Harm (http://stemcellresearch.org/statement/pptalkingpointsweb.pdf) refuting that, and don't know how to reconcile the two.

 
At May 01, 2009 , Blogger Wesley J. Smith said...

Michele: Absolutely not. They are stem cells. To call them embryos, which is what is made via cloning is ludicrous. They can differentiate into tissues, they cannot on their own become a whole new organism.

A lot of sophistry going on to confuse people into being unable to make crucial ethical distinctions and to think critically.

Some believe that IPSCs could be used to create clones. But until that happened, they are not clones. Skin cells can be used to make clones too. They are not cloned embryos either.

Remember, also, we are speaking of human life. A human being does not reproduce like a single cell bacterium. When our cells divide, they are not reproducing the orgnaism, they are making new cells of the kind that is dividing.

 

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