Monday, August 11, 2008

Lead into Gold: New Patient-Specific Stem Cell Lines Created from Patients With Genetic Diseases

Remember when the above headline was breathlessly expected to come from human cloning and to serve as a repudiation of the Bush stem cell funding policy? This breakthrough, however, came about with induced pluripotent stem cells created from patient skin cells and bone marrow. From the story:

Harvard scientists made the announcement on Thursday that they have developed 20 new stem cell lines which could lead to treatments and cures for diseases such as Parkinson’s Down Syndrome, diabetes, etc.The new stem cell lines were taken from patients who already had a genetic illness, and are based on regular skin cells and bone marrow.
Yes, yes, I know: ESCR was needed to develop iPSCs. But most, if not all, of that research was done with Bush approved cell lines. Moreover, as I have argued, I believe that Bush's focus on the moral importance of the human embryo created the atmosphere in which scientists kept searching for ethical ways to obtain the benefits of pluripotent stem cells--a continuing saga which should bring us even better news in the months and years to come.

Here's the point: iPSCs are doing now what the brave new world types promised therapeutic cloning would do in about a decade. No wonder the stem cell controversy isn't one in the current election.

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1 Comments:

At August 11, 2008 , Blogger Dark Swan said...

Very nice Wesley.

It is good to see an acknowledgment of the historical progression from ESCr to iPSC. Hopefully the future of these lines will lead to cures for the diseases they carry.

The efforts of scientists researching pluripotent technology responsibly and ethically lead to processes which are socially acceptable to various viewpoints.

I agree, It appears iPSC has lead to a drawback from hostile engagements between scientists and pro-lifers, which is obviously a good thing. However many scientists are pro-life and I'm sure they are happy to reach a mutual agreement as well.

Of interest here, Chad Cowan, one of the primary scientist contributing to this research at Harvard is operating as an Investigator for the Stowers Medical Institute.

http://www.stowersmedicalinstitute.org/whatsnew/2008/pr080708.asp

I think the Stowers deserve some credit for investing in the future of peoples health and happiness.

I expect their Investigator's research to lead to many great things in the future.

 

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