Holy Cow: "Cybrids" Manufactured in UK
Scientists in the UK claim to have made embryos using cow eggs and human DNA through SCNT. Although the work has yet to be verified via peer review, Newcastle scientists told the press that the embryos lasted three days. From the story:
Embryos containing both human and animal material have been created in Britain for the first time, a month before the House of Commons is to vote on new laws to regulate the controversial research. A team at the University of Newcastle-upon-Tyne announced tonight that it had successfully generated "admixed embryos" by adding human DNA to empty cow eggs, in the first experiment of its kind in the UK. The achievement will heighten debate over the ethics of human-animal embryos, as the Commons prepares to debate the Human Fertilisation and Embryology Bill next month.
Admixed embryos are widely supported by the scientific community and patient groups, as they provide an opportunity to produce powerful stem cell models for investigating diseases such as Parkinson's and diabetes, and for developing new drugs.
Their creation, however, has been vociferously opposed by religious groups, particularly the Roman Catholic church. Cardinal Keith O'Brien, the head of the Catholic church in Scotland, described the work last month as "experiments of Frankenstein proportion"...Once the technique has been tested, scientists hope to create cybrids from the DNA of patients with genetic diseases. The resulting stem cells could then be used as models of those diseases to provide insights into their progress and to test new treatments.
But the new IPSCs could do that too, and without the effort, expense, and moral contentiousness involved in trying to develop cloning techniques. Indeed, the scientist in charge of the team who created Dolly, Ian Wilmut, gave up cloning research that he had been licensed to perform precisely because of the "lead into gold" IPSC breakthrough.
I find it remarkable that the reporter didn't raise this question with the scientists. If we can obtain the benefits they claim to be pursuing without compromising crucial moral principles, why wouldn't we? Perhaps because, as I suspect, the real point of this is to learn to clone human life come what may.
Labels: Human/Animal Cybrid Embryos


7 Comments:
Wesley, have you written an argument against the morality of human cloning anywhere? If so, will you please direct me to it? Thanks.
Hey, Lincoln: Long time no hear from. My book Consumer's Guide to a Brave New World is the most extended on that question. I have written articles on it, too. Go to the archives and see what you find. I find the ideas of Leon Kass and Bill Hurlbut on these issues quite persuasive. Thanks for asking.
How "empty" are the cow eggs? If they have mitochondria, they have their own bovine DNA.
If they were making human/cow chimeras (maybe not the right technical term) to study Parkinson's or whatever, why would they think that what they learn will transfer to actual humans?
Wesley, in 2000 or so, Austrailian researchers created what you've noted First Things editor Joseph Bottum called the Pig Man. The researchers inserted human DNA/cells into a pig's egg and let it grow a bit before killing it. I think the same has been done with rabbit eggs in China. Is there anything new about this here? I suspect the reason is new-women are not willing to lay their bodies down for research for nothing and they need eggs, but is there something new in this, or just more of the same, but in Britain?
Don: I loved Jody's "The Pigman Cometh," a superb polemical rant. The China and Australian studies have never been verified. The UK hasn't either, yet, although it might well be.
But I don't see the scientific need for this cloning with the IPSCs coming on line.
Thanks Wesley. I don't see the need either because of IPSCs. Maureen Condic has a post at Do No Harm that says these should be superior cells. So there's something more here. We aren't supposed to tamper with human life UNLESS all other alternatives have been exhausted. Well, at least we used to believe that as recently as President Bill Clinton's bioethics advisory board. I think this is what we should expect from a science/culture that rejects human exceptionalism. Nothing is off limits or non arbitrarily off limits if humans are not exceptional by viture of being human.
Died after three days. I'm still laying my bets on all such cybrid embryos being non-viable in the strict sense that they die _real_ early, spontaneously. DNA is far, far from everything in early embryonic development.
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